"Sabbe sankhara anicca" ti yada pannaya passati atha nibbindati dukkhe esa maggo visuddhiya.
"All conditioned phenomena are impermanent"; when one sees this with Insight-wisdom, one becomes weary of dukkha (i.e., the khandhas). This is the Path to Purity. - Dhammapada 277
"All born, formed, made, conditioned things (five aggregates) are impermanent"—when one gains insight into this through wisdom, one becomes disillusioned with the unsatisfactory nature of five aggregates. This is the very path toward nibbana.
"Sabbe sankhara dukkha" ti yada pannaya passati atha nibbindati dukkhe esa maggo visuddhiya.
"All conditioned phenomena are dukkha"; when one sees this with Insight-wisdom, one becomes weary of dukkha (i.e., the khandhas). This is the Path to Purity. -Dhammapada 278
"All born, formed, made, and conditioned things are unsatisfactory"—when one gains insight into this through wisdom, one becomes disillusioned with the unsatisfactory nature of five aggregates that are impermanent. This understanding is the very path to nibbana.
"Sabbe sankhara anatta" ti yada pannaya passati atha nibbindati dukkhe esa maggo visuddhiya.
"All phenomena (dhammas) are without Self"; when one sees this with Insight-wisdom, one becomes weary of dukkha (i.e., the khandhas). This is the Path to Purity. - Dhammapada 279
Thus, "All born, formed, made, and conditioned things are without a permanent self (soul)"—when one perceives this with wisdom, one is freed from dukkha; this is the path toward nibbana.
Dukkha : unsatisfactory state
Khandhas : five aggregates
* Dukkha = unsatisfactory nature of Khandhas (all conditioned things) that are anicca (impermanent) and anatta (not-self)